Who can inject Botox? The rules, state by state

Last checked October 25, 2026. Information, not legal advice.

Physicians can inject Botox in every state we cover. Physician assistants and nurse practitioners can too, within their own license and their state's supervision or collaboration rules. Registered nurses can inject in every state we cover, but only with conditions: a physician, NP or PA typically examines the patient and orders the treatment first, and the state decides who must supervise. LPNs, medical assistants and estheticians are where the states split most.

The rules side by side

This table shows Botox (neurotoxins) only. Fillers, the exact conditions and the sources are in each state's guide; click the state name.

StateRNNPLPN / LVNMedical assistantEsthetician
CaliforniaYes, with conditionsYes, with conditionsNoNoNo
TexasYes, with conditionsYes, with conditionsYes, with conditionsNot addressedNo
FloridaYes, with conditionsYes, with conditionsNot addressedNot addressedNo
New YorkYes, with conditionsYes, with conditionsNot addressedNoNo
ArizonaYes, with conditionsYes, with conditionsNoNot addressedNo
GeorgiaYes, with conditionsYes, with conditionsNoNot addressedNo
IllinoisYes, with conditionsYes, with conditionsNot addressedNoNo
New JerseyYes, with conditionsYes, with conditionsNot addressedNot addressedNo
North CarolinaYes, with conditionsYes, with conditionsYes, with conditionsNot addressedNo
ColoradoYes, with conditionsYes, with conditionsNot addressedYes, with conditionsYes, with conditions

"Not addressed" means we found no statute, rule or board statement that answers the question for that role. It does not mean the role is allowed.

What "with conditions" usually means

  • An exam first. Before a nurse injects, a prescriber usually has to assess the patient. Who counts as that prescriber differs: in Florida, the board's rulings require a physician (MD or DO), not an NP, to delegate and supervise an RN's Botox injections.
  • An order. The nurse acts on an order from a prescriber. Some states require a patient-specific order; New York's standing-order law does not cover cosmetic injectables, for example.
  • Supervision or delegation rules. States set who supervises and how closely. North Carolina lets an RN inject with no prescriber on site, while an LPN there needs an RN or a prescriber on site.
  • Your own license. No state lets a license stretch to cover work outside it. An esthetician license alone never covers injections in the states we cover.

Where the states differ most

LPNs and LVNs

North Carolina and Texas allow LPN or LVN injections with conditions. California, Arizona and Georgia say no. In several other states we found no rule either way, so check your state's guide before you take a job.

Estheticians

The esthetician license does not cover Botox or fillers in any state we cover. Colorado is the exception that comes closest: its Medical Board rules let a physician delegate injections to a trained person, which can include an esthetician acting as the physician's delegate, not under the esthetician license. Read Can estheticians do Botox? for the details.

Medical assistants

California, Illinois and New York say medical assistants may not inject Botox. Colorado allows it only as a physician's delegate. For the other states we cover, we did not find a direct board statement in the sources we reviewed.

How to use these guides

Each guide lists its sources and the date we last checked them. Rules change, and boards decide close cases one at a time. If your situation is unusual, ask your board or a health care attorney before you treat patients.

Read your state's guide